Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IF
Concentration
1 mg/ml
Recomended Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MAD1. AA range:394-443
Subcellular Location
Nucleus . Chromosome, centromere, kinetochore . Nucleus envelope . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, spindle pole . Co-localizes with TPR at the nucleus envelop
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
8379
Other Name
HsMAD1
MAD1
MAD1-like protein 1
MAD1L1
Mitotic arrest deficient 1-like protein 1
Mitotic checkpoint MAD1 protein homolog
Mitotic spindle assembly checkpoint protein MAD1
TXBP181
Tax-binding protein 181
hMAD1
MAD1
MAD1-like protein 1
MAD1L1
Mitotic arrest deficient 1-like protein 1
Mitotic checkpoint MAD1 protein homolog
Mitotic spindle assembly checkpoint protein MAD1
TXBP181
Tax-binding protein 181
hMAD1
Background
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cel