Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Dysferlin. AA range:1981-2030
Subcellular Location
Cell membrane, sarcolemma
Single-pass type II membrane protein . Cell membrane. Colocalizes, during muscle differentiation, with BIN1 in the T-tubule system of myotubules and at the site of contact between two myotubes or a myoblast and a myotube. Wounding of myotubes led to its f
Single-pass type II membrane protein. Cytoplasmic vesicle membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
8291
Observed Band
240kD
Other Name
DYSF
Dysferlin
Dystrophy-associated fer-1-like protein
FER1L1
Fer-1-like protein 1
Background
dysferlin(DYSF) Homo sapiens The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-m