Información del producto
SMC1 (phospho Ser957) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SMC1 around the phosphorylation site of Ser957. AA range:931-980
Subcellular Location
Nucleus . Chromosome . Chromosome, centromere, kinetochore . Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
8243
Observed Band
143kD
Other Name
DXS423E
KIAA0178
SB1.8
SMC-1-alpha
SMC-1A
SMC1
SMC1A
SMC1L1
SMC protein 1A
Sb1.8
Structural maintenance of chromosomes protein 1A
KIAA0178
SB1.8
SMC-1-alpha
SMC-1A
SMC1
SMC1A
SMC1L1
SMC protein 1A
Sb1.8
Structural maintenance of chromosomes protein 1A
Background
structural maintenance of chromosomes 1A(SMC1A) Homo sapiens Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohes