Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TFEB. AA range:10-59
Subcellular Location
Cytoplasm, cytosol . Lysosome membrane . Nucleus . Mainly present in the cytoplasm (PubMed:23434374, PubMed:33691586). Under aberrant lysosomal storage conditions, it translocates from the cytoplasm to the nucleus (PubMed:21617040, PubMed:22576015, PubMed
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
7942
Observed Band
52kD
Other Name
BHLHE35
Class E basic helix-loop-helix protein 35
TFEB
Transcription factor EB
bHLHe35
Class E basic helix-loop-helix protein 35
TFEB
Transcription factor EB
bHLHe35
Background
function:Probable transcription factor binds to the USF/MLTF site and probably recognizes E-box sequences in the heavy-chain immunoglobulin enhancer.,similarity:Belongs to the MiT/TFE family.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,sub