Información del producto
Fusin (phospho Ser339) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CXCR4 around the phosphorylation site of Ser339. AA range:303-352
Subcellular Location
Cell membrane
Multi-pass membrane protein . Cell junction. Early endosome. Late endosome. Lysosome. In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated. In the pr
Multi-pass membrane protein . Cell junction. Early endosome. Late endosome. Lysosome. In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated. In the pr
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Rat
Monkey
Mouse
Rat
Human Gen
7852
Observed Band
38kD
Other Name
C-X-C chemokine receptor type 4
CD antigen CD184
CXC-R4
CXCR-4
CXCR4
FB22
Fusin
HM89
LCR1
LESTR
Leukocyte-derived seven transmembrane domain receptor
NPYRL
SDF-1 receptor
Stromal cell-derived factor 1 receptor
CD antigen CD184
CXC-R4
CXCR-4
CXCR4
FB22
Fusin
HM89
LCR1
LESTR
Leukocyte-derived seven transmembrane domain receptor
NPYRL
SDF-1 receptor
Stromal cell-derived factor 1 receptor
Background
C-X-C motif chemokine receptor 4(CXCR4) Homo sapiens This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to supp