Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CA II. AA range:180-229
Subcellular Location
Cytoplasm . Cell membrane . Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Rat
Human Gen
760
Observed Band
29kD
Other Name
CA-II
CA2
CAC
Carbonate dehydratase II
Carbonic anhydrase 2
Carbonic anhydrase C
Carbonic anhydrase II
CA2
CAC
Carbonate dehydratase II
Carbonic anhydrase 2
Carbonic anhydrase C
Carbonic anhydrase II
Background
The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encodin