Información del producto
Tuberin (phospho Thr1462) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Tuberin/TSC2 around the phosphorylation site of Thr1462. AA range:1428-1477
Subcellular Location
Cytoplasm. Membrane
Peripheral membrane protein. At steady state found in association with membranes.
Peripheral membrane protein. At steady state found in association with membranes.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
7249
Observed Band
200kD
Other Name
TSC2
TSC4
Tuberin
Tuberous sclerosis 2 protein
TSC4
Tuberin
Tuberous sclerosis 2 protein
Background
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for ham