Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TNF Receptor I. AA range:381-430
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Golgi apparatus membrane
Single-pass type I membrane protein . Secreted . A secreted form is produced through proteolytic processing.
[Isoform 4]: Secreted. Lacks a Golgi-retention motif, is not membrane bound and therefore is secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
7132
Observed Band
50kD
Other Name
CD antigen CD120a
TNF-R1
TNF-RI
TNFAR
TNFR-I
TNFR1
TNFRSF1A
Tumor necrosis factor receptor 1
Tumor necrosis factor receptor superfamily member 1A
Tumor necrosis factor receptor type I
p55
p60
Background
This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Bindin