Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor III around the phosphorylation site of Thr842. AA range:801-850
Subcellular Location
Secreted. Secreted, extracellular space. Cell membrane
Single-pass type I membrane protein . Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
7049
Other Name
Betaglycan
TGF-beta receptor type 3
TGF-beta receptor type III
TGFBR3
TGFR-3
Transforming growth factor beta receptor III
Transforming growth factor beta receptor type 3
Background
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TG