Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TGF beta Receptor II around the phosphorylation site of Ser225/250. AA range:191-240
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Membrane raft .
[Isoform 3]: Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
7048
Observed Band
75kD
Other Name
TGF-beta receptor type-2
TGF-beta receptor type II
TGF-beta type II receptor
TGFBR2
TGFR-2
TbetaR-II
Transforming growth factor-beta receptor type II
Background
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-be