Información del producto
Tie-2 (phospho Tyr1102) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TIE2 around the phosphorylation site of Tyr1102. AA range:1068-1117
Subcellular Location
Cell membrane
Single-pass type I membrane protein. Cell junction . Cell junction, focal adhesion . Cytoplasm, cytoskeleton. Secreted . Recruited to cell-cell contacts in quiescent endothelial cells (PubMed:18425120, PubMed:18425119). Colocalizes with the actin cytoskel
Single-pass type I membrane protein. Cell junction . Cell junction, focal adhesion . Cytoplasm, cytoskeleton. Secreted . Recruited to cell-cell contacts in quiescent endothelial cells (PubMed:18425120, PubMed:18425119). Colocalizes with the actin cytoskel
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
7010
Other Name
Angiopoietin-1 receptor
Endothelial tyrosine kinase
TEK
TIE2
Tunica interna endothelial cell kinase
Tyrosine-protein kinase receptor
Tyrosine-protein kinase receptor TEK
Tyrosine kinase with Ig and EGF homology domains-2
VMCM
VMCM1
Endothelial tyrosine kinase
TEK
TIE2
Tunica interna endothelial cell kinase
Tyrosine-protein kinase receptor
Tyrosine-protein kinase receptor TEK
Tyrosine kinase with Ig and EGF homology domains-2
VMCM
VMCM1
Background
This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fib