Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MUNC-18a around the phosphorylation site of Ser313. AA range:279-328
Subcellular Location
Cytoplasm, cytosol . Membrane
Peripheral membrane protein.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Rat
Human Gen
6812
Observed Band
65kD
Other Name
MUNC18-1
N-Sec1
Protein unc-18 homolog 1
Protein unc-18 homolog A
STXBP1
Syntaxin-binding protein 1
UNC18A
Unc-18A
Unc18-1
p67
Background
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile ep