Información del producto
Krs-1/2 (phospho Thr183) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Mst1/2 around the phosphorylation site of Thr183. AA range:149-198
Subcellular Location
Cytoplasm . Nucleus . The caspase-cleaved form cycles between nucleus and cytoplasm (PubMed:19525978, PubMed:11278283). Phosphorylation at Thr-117 leads to inhibition of nuclear translocation (PubMed:19525978). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
6789
Observed Band
60kD
Other Name
KRS1
KRS2
MST-2
MST1
MST2
Mammalian STE20-like prot
Mammalian STE20-like protein kinase 2
STE20-like kinase MST2
STK3
STK4
Serine/threonine-protein kinase 3
Serine/threonine-protein kinase 4
Serine/threonine-protein kinase Krs-1
KRS2
MST-2
MST1
MST2
Mammalian STE20-like prot
Mammalian STE20-like protein kinase 2
STE20-like kinase MST2
STK3
STK4
Serine/threonine-protein kinase 3
Serine/threonine-protein kinase 4
Serine/threonine-protein kinase Krs-1
Background
serine/threonine kinase 3(STK3) Homo sapiens This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the