Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ALS2CR4. AA range:181-230
Subcellular Location
Membrane
Multi-pass membrane protein . Cell projection, cilium . Localizes at the proximal region of primary cilia were observed, consistent with localization to the transition zone. Anchored to the transition zone by RPGRIP1L.
Multi-pass membrane protein . Cell projection, cilium . Localizes at the proximal region of primary cilia were observed, consistent with localization to the transition zone. Anchored to the transition zone by RPGRIP1L.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
65062
Observed Band
48kD
Other Name
ALS2CR4
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein
TMEM237
Transmembrane protein 237
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein
TMEM237
Transmembrane protein 237
Background
The protein encoded by this gene is a tetraspanin protein that is thought to be involved in WNT signaling. Defects in this gene are a cause of Joubert syndrome-14. Two transcript variants encoding different isoforms have been found for this gene. [provide