Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human CD318 (phospho Tyr707)
Subcellular Location
Single-pass membrane protein . Shedding may also lead to a soluble peptide.
[Isoform 1]: Cell membrane
[Isoform 3]: Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
64866
Observed Band
140,80kD
Other Name
CDCP1
CD antigen CD318
CUB domain-containing protein 1
Membrane glycoprotein gp140
SIMA135
Subtractive immunization M plus HEp3-associated 135 kDa protein
TRASK
Transmembrane and associated with src kinases
Background
This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in