Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human RFWD2. AA range:353-402
Subcellular Location
Nucleus speckle. Cytoplasm. In the nucleus, it forms nuclear speckles.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
64326
Observed Band
110kD
Other Name
COP1
Constitutive photomorphogenesis protein 1 homolog
E3 ubiquitin-protein ligase RFWD2
RFWD2
RING finger and WD repeat domain protein 2
RING finger protein 200
RNF200
hCOP1
Constitutive photomorphogenesis protein 1 homolog
E3 ubiquitin-protein ligase RFWD2
RFWD2
RING finger and WD repeat domain protein 2
RING finger protein 200
RNF200
hCOP1
Background
domain:The RING finger domain, in addition to its role in ubiquitination, functions as a structural scaffold to bring two clusters of positive-charged residues within spatial proximity to mimic a bipartite nuclear localization signal (NLS).,function:E3 ub
protein ubiquitination.,similarity:Belongs to the COP1 family.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 7 WD repeats.,subcellular location:In the nucleus, it forms nuclear speckles.,subunit:Homodimer. Homodimerization is mediated b
protein ubiquitination.,similarity:Belongs to the COP1 family.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 7 WD repeats.,subcellular location:In the nucleus, it forms nuclear speckles.,subunit:Homodimer. Homodimerization is mediated b