Información del producto
Na+ CP type VIIα rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SCN7A. AA range:771-820
Subcellular Location
Cell membrane
Multi-pass membrane protein .
Multi-pass membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Monkey
Human Gen
6332
Observed Band
200kD
Other Name
Putative voltage-gated sodium channel subunit alpha Nax
SCN6A
SCN7A
Sodium channel protein cardiac and skeletal muscle subunit alpha
Sodium channel protein type 7 subunit alpha
Sodium channel protein type VII subunit alpha
SCN6A
SCN7A
Sodium channel protein cardiac and skeletal muscle subunit alpha
Sodium channel protein type 7 subunit alpha
Sodium channel protein type VII subunit alpha
Background
This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel pro
domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011],
the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels
domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011],
the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels