Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CFAB Bb. AA range:241-290
Subcellular Location
Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
629
Observed Band
57+85kD
Other Name
BF
BFD
C3/C5 convertase
CFB
Complement factor B
GBG
Glycine-rich beta glycoprotein
PBF2
Properdin factor B
Background
This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yieldi