Información del producto
p70 S6 kinase α (phospho Thr421) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human p70 S6 kinase α (phospho Thr421)
Subcellular Location
Cell junction, synapse, synaptosome . Mitochondrion outer membrane. Mitochondrion. Colocalizes with URI1 at mitochondrion.
[Isoform Alpha II]: Cytoplasm.
[Isoform Alpha I]: Nucleus. Cytoplasm.
[Isoform Alpha II]: Cytoplasm.
[Isoform Alpha I]: Nucleus. Cytoplasm.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
6198
Observed Band
70kD
Other Name
70 kDa ribosomal protein S6 kinase 1
P70S6K1
RPS6KB1
Ribosomal protein S6 kinase I
Ribosomal protein S6 kinase beta-1
S6K-beta-1
S6K1
STK14A
Serine/threonine-protein kinase 14A
p70 S6 kinas
p70 ribosomal S6 kinase alpha
p70-S6K 1
P70S6K1
RPS6KB1
Ribosomal protein S6 kinase I
Ribosomal protein S6 kinase beta-1
S6K-beta-1
S6K1
STK14A
Serine/threonine-protein kinase 14A
p70 S6 kinas
p70 ribosomal S6 kinase alpha
p70-S6K 1
Background
ribosomal protein S6 kinase B1(RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis,