Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human BAX. AA range:80-129
Subcellular Location
Single-pass membrane protein . Cytoplasm . Colocalizes with 14-3-3 proteins in the cytoplasm. Under stress conditions, undergoes a conformation change that causes release from JNK-phosphorylated 14-3-3 proteins and translocation to the mitochondrion membr
[Isoform Alpha]: Mitochondrion outer membrane
[Isoform Beta]: Cytoplasm.
[Isoform Delta]: Cytoplasm .
[Isoform Gamma]: Cytoplasm.
[Isoform Alpha]: Mitochondrion outer membrane
[Isoform Beta]: Cytoplasm.
[Isoform Delta]: Cytoplasm .
[Isoform Gamma]: Cytoplasm.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Chicken
Human
Mouse
Rat
Human
Mouse
Rat
Human Gen
581
Observed Band
22kD
Background
The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.