Información del producto
Bax (phospho Thr167) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IF
Concentration
1 mg/ml
Recomended Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Thr167. AA range:133-182
Subcellular Location
Single-pass membrane protein . Cytoplasm . Colocalizes with 14-3-3 proteins in the cytoplasm. Under stress conditions, undergoes a conformation change that causes release from JNK-phosphorylated 14-3-3 proteins and translocation to the mitochondrion membr
[Isoform Alpha]: Mitochondrion outer membrane
[Isoform Beta]: Cytoplasm.
[Isoform Delta]: Cytoplasm .
[Isoform Gamma]: Cytoplasm.
[Isoform Alpha]: Mitochondrion outer membrane
[Isoform Beta]: Cytoplasm.
[Isoform Delta]: Cytoplasm .
[Isoform Gamma]: Cytoplasm.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
581
Other Name
Apoptosis regulator BAX
BAX
BCL2L4
Bcl-2-like protein 4
Bcl2-L-4
BAX
BCL2L4
Bcl-2-like protein 4
Bcl2-L-4
Background
The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.