Información del producto
SH-PTP1 (phospho Tyr536) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SHP-1 around the phosphorylation site of Tyr536. AA range:502-551
Subcellular Location
Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5777
Observed Band
67kD
Other Name
HCP
Hematopoietic cell protein-tyrosine phosphatase
PTP-1C
PTP1C
PTPN6
Protein-tyrosine phosphatase 1C
Protein-tyrosine phosphatase SHP-1
SH-PTP1
Tyrosine-protein phosphatase non-receptor type 6
Hematopoietic cell protein-tyrosine phosphatase
PTP-1C
PTP1C
PTPN6
Protein-tyrosine phosphatase 1C
Protein-tyrosine phosphatase SHP-1
SH-PTP1
Tyrosine-protein phosphatase non-receptor type 6
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic tran