Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human HECW2. AA range:481-530
Subcellular Location
Cytoplasm . Cytoplasm, cytoskeleton, spindle .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
57520
Observed Band
140-150kD
Other Name
C2 and WW domain-containing protein 2
E3 ubiquitin-protein ligase HECW2
HECT
HECW2
KIAA1301
NEDD4-like E3 ubiquitin-protein ligase 2
NEDL2
E3 ubiquitin-protein ligase HECW2
HECT
HECW2
KIAA1301
NEDD4-like E3 ubiquitin-protein ligase 2
NEDL2
Background
function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.,pathway:Protein modification
protein ubiquitination.,similarity:Contains 1 C2 domain.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 2 WW domains.,subunit:Interacts with TP73.,tissue specificity:Predominantly expressed in adult brain, l
protein ubiquitination.,similarity:Contains 1 C2 domain.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 2 WW domains.,subunit:Interacts with TP73.,tissue specificity:Predominantly expressed in adult brain, l