Información del producto
ATRIP (phospho Ser224) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ATRIP around the phosphorylation site of Ser224. AA range:190-239
Subcellular Location
Nucleus . Redistributes to discrete nuclear foci upon DNA damage.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
84126
Observed Band
86kD
Other Name
AGS1
ATM and Rad3-related-interacting protein
ATR-interacting protein
ATRIP
ATM and Rad3-related-interacting protein
ATR-interacting protein
ATRIP
Background
This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting