Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human RBBP8. AA range:630-679
Subcellular Location
Nucleus . Chromosome . Associates with sites of DNA damage in S/G2 phase (PubMed:10764811, PubMed:25349192). Ubiquitinated RBBP8 binds to chromatin following DNA damage (PubMed:16818604). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
5932
Other Name
CTIP
CtBP-interacting protein
CtIP
DNA endonuclease RBBP8
RBBP-8
RBBP8
RIM
Retinoblastoma-binding protein 8
Retinoblastoma-interacting protein and myosin-like
SAE2
Sporulation in the absence of SPO11 protein 2 homolog
Background
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTB