Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PTPRN2. AA range:206-255
Subcellular Location
Cytoplasmic vesicle, secretory vesicle membrane
Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Single-pass type I membrane protein . Predominantly found on dense-core secretory granules. Sorting to secretory granules in part is dependent of the N-terminal propeptide domain of the precursor and its interaction with CPE (By similarity). Transiently f
[IA-2beta60]: Cytoplasmic vesicle, secretory vesicle membrane .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5799
Observed Band
111kD
Other Name
IAR
ICAAR
Islet cell autoantigen-related protein
KIAA0387
PTPRN2
Phogrin
R-PTP-N2
Receptor-type tyrosine-protein phosphatase N2
Background
This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protei