Información del producto
Brk (phospho Tyr447) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Breast Tumor Kinase around the phosphorylation site of Tyr447. AA range:402-451
Subcellular Location
Cytoplasm. Nucleus. Cell projection, ruffle. Membrane . Colocalizes with KHDRBS1, KHDRBS2 or KHDRBS3, within the nucleus. Nuclear localization in epithelial cells of normal prostate but cytoplasmic localization in cancer prostate.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5753
Observed Band
50kD
Other Name
BRK
Breast tumor kinase
PTK6
Protein-tyrosine kinase 6
Tyrosine-protein kinase BRK
Breast tumor kinase
PTK6
Protein-tyrosine kinase 6
Tyrosine-protein kinase BRK
Background
protein tyrosine kinase 6(PTK6) Homo sapiens The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial