Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC4A8/10. AA range:411-460
Subcellular Location
Membrane
Multi-pass membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
57282/9498
Observed Band
140kD
Other Name
Electroneutral Na(+)-driven Cl-HCO3 exchanger
Electroneutral sodium bicarbonate exchanger 1
KIAA0739
NBC
NBC3
NCBE
NDCBE1
SLC4A8
SLC4A10
Sodium-driven chloride bicarbonate exchanger
Solute
Solute carrier family 4 member 8
k-NBC3
Background
The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-D