Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PAK5/6 around the phosphorylation site of Ser602/Ser560. AA range:566-615
Subcellular Location
Mitochondrion. Cytoplasm. Nucleus. Shuttles between the nucleus and the mitochondria, and mitochondrial localization is essential for the role in cell survival.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
57144/56924
Observed Band
75kD
Other Name
KIAA1264
PAK-5
PAK-5
PAK-6
PAK-7
PAK5
PAK5
PAK6
PAK7
Serine/threonine-protein kinase PAK 6
Serine/threonine-protein kinase PAK 7
p21-activated kinase 5
p21-activated kinase 6
p21-activated kinase 7
Background
The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell su