Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PLXDC1. AA range:71-120
Subcellular Location
Single-pass type I membrane protein. Cell junction, tight junction. Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted .
[Isoform 3]: Secreted .
[Isoform 4]: Cytoplasm .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
57125
Other Name
PLXDC1
Plexin domain-containing protein 1
TEM3
TEM7
Tumor endothelial marker 3
Tumor endothelial marker 7
Background
PTM:N-glycosylated.,similarity:Belongs to the plexin family.,subunit:May interact with cortactin.,tissue specificity:Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast a