Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PSMD3. AA range:351-400
Subcellular Location
proteasome complex,nucleus,nucleoplasm,cytoplasm,cytosol,proteasome regulatory particle, lid subcomplex,membrane,proteasome accessory complex,extracellular exosome,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5709
Observed Band
61kD
Other Name
26S proteasome non-ATPase regulatory subunit 3
26S proteasome regulatory subunit RPN3
26S proteasome regulatory subunit S3
PSMD3
Proteasome subunit p58
Background
2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits