Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human FMN2. AA range:1541-1590
Subcellular Location
Cytoplasm, cytoskeleton . Cytoplasm, cytosol . Cytoplasm, perinuclear region . Nucleus . Nucleus, nucleolus . Cell membrane
Cytoplasmic side . Cytoplasm, cell cortex . Colocalizes with the actin cytoskeleton (PubMed:20082305). Recruited to the membranes via its interaction with SPIRE1 (By similarity). Detected at the cleavage furrow during asymmetric oocyte division and polar
Cytoplasmic side . Cytoplasmic vesicle membrane
Peripheral membrane protein
Peripheral membrane protein
Cytoplasmic side . Cytoplasm, cell cortex . Colocalizes with the actin cytoskeleton (PubMed:20082305). Recruited to the membranes via its interaction with SPIRE1 (By similarity). Detected at the cleavage furrow during asymmetric oocyte division and polar
Cytoplasmic side . Cytoplasmic vesicle membrane
Peripheral membrane protein
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
56776
Other Name
FMN2
Formin-2
Formin-2
Background
This gene is a member of the formin homology protein family. The encoded protein is thought to have essential roles in organization of the actin cytoskeleton and in cell polarity. Mutations in this gene have been associated with mental retardation autosom