Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Presenilin 2 around the phosphorylation site of Ser330. AA range:296-345
Subcellular Location
Endoplasmic reticulum membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Golgi apparatus membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5664
Observed Band
50kD
Other Name
AD3LP
AD4
AD5
E5-1
PS-2
PS2
PSEN2
PSNL2
Presenilin-2
STM-2
STM2
Background
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of