Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MAP2K7 around the phosphorylation site of Thr275. AA range:241-290
Subcellular Location
Nucleus. Cytoplasm .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5609
Observed Band
43kD
Other Name
Dual specificity mitogen-activated protein kinase kinase 7
JNK-activating kinase 2
JNKK2
MAP2K7
MAPK/ERK kinase 7
MAPKK 7
MAP kinase kinase 7
MEK7
MEK 7
MKK7
PRKMK7
S
SAPK kinase 4
SKK4
Stress-activated protein kinase kinase 4
Background
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase k