Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Girdin around the phosphorylation site of Ser1417. AA range:1383-1432
Subcellular Location
Cell membrane
Peripheral membrane protein . Cytoplasm, cytosol . Cytoplasmic vesicle . Cell projection, lamellipodium . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localizes to the cytosol
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
55704
Other Name
APE
APE
Akt phosphorylation enhancer
CCDC88A
Coiled-coil domain-containing protein 88A
GIV
GRDN
G alpha-interacting vesicle-associated protein
Girders of actin filament
Girdin
HkRP1
Hook-related protein 1
KIAA1212
Background
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration.