Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC39A4. AA range:431-480
Subcellular Location
Cell membrane
Multi-pass membrane protein . Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.
Multi-pass membrane protein . Recycling endosome membrane
Multi-pass membrane protein . Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.
Multi-pass membrane protein . Recycling endosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
55630
Observed Band
68kD
Other Name
SLC39A4
Solute carrier family 39 member 4
ZIP-4
ZIP4
Zinc transporter ZIP4
Zrt- and Irt-like protein 4
Solute carrier family 39 member 4
ZIP-4
ZIP4
Zinc transporter ZIP4
Zrt- and Irt-like protein 4
Background
This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica. M