Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PPP1R8. AA range:196-245
Subcellular Location
Nucleus. Nucleus speckle. Primarily, but not exclusively, nuclear.
[Isoform Gamma]: Cytoplasm. Found mainly in the cytoplasm.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5511
Observed Band
40kD
Other Name
ARD1
NIPP-1
NIPP1
Nuclear inhibitor of protein phosphatase 1
PPP1R8
Protein phosphatase 1 regulatory inhibitor subunit 8
Background
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform