Storage Conditions
-20°C/1 year
Applications
ELISA
IF
Concentration
1 mg/ml
Recomended Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TM16A. AA range:921-970
Subcellular Location
Cell membrane
Multi-pass membrane protein . Cytoplasm . Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
55107
Other Name
ANO1
Anoctamin-1
DOG1
Discovered on gastrointestinal stromal tumors protein 1
ORAOV2
Oral cancer overexpressed protein 2
TAOS2
TMEM16A
Transmembrane protein 16A
Tumor-amplified and overexpressed sequence 2
Background
domain:The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region.,function:Acts as a calcium-activated chloride channel. Required for normal tracheal development.,similarity:Belongs to the anoctamin family.,tissu