Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from Atg16 . at AA range: 60-140
Subcellular Location
Cytoplasm . Preautophagosomal structure membrane
Peripheral membrane protein . Endosome membrane
Peripheral membrane protein . Lysosome membrane
Peripheral membrane protein . Recruited to omegasomes membranes by WIPI2 (By similarity). Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures (By similarity). Localized to preautophagosomal structure (PAS
Peripheral membrane protein . Endosome membrane
Peripheral membrane protein . Lysosome membrane
Peripheral membrane protein . Recruited to omegasomes membranes by WIPI2 (By similarity). Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures (By similarity). Localized to preautophagosomal structure (PAS
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
55054
Observed Band
70kD
Other Name
APG16-like 1
APG16L
ATG16L1
Autophagy-related protein 16-1
APG16L
ATG16L1
Autophagy-related protein 16-1
Background
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to infla