Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human 40603.
Subcellular Location
Golgi apparatus, trans-Golgi network membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Cytoplasmic vesicle membrane
Multi-pass membrane protein . Early endosome membrane
Multi-pass membrane protein . Late endosome membrane
Multi-pass membrane protein . Lysosome membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Cytoplasmic vesicle membrane
Multi-pass membrane protein . Early endosome membrane
Multi-pass membrane protein . Late endosome membrane
Multi-pass membrane protein . Lysosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
55016
Observed Band
32kD
Other Name
E3 ubiquitin-protein ligase MARCH1
MARCH-I
MARCH1
Membrane-associated RING-CH protein I
Membrane-associated RING finger protein 1
RING finger protein 171
RNF171
MARCH-I
MARCH1
Membrane-associated RING-CH protein I
Membrane-associated RING finger protein 1
RING finger protein 171
RNF171
Background
De Gassart et al., 2008 [PubMed 18305173]).[supplied by OMIM, Mar 2010],
MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments.
Thibodeau et al., 2008 [PubMed 18389477]
MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments.
Thibodeau et al., 2008 [PubMed 18389477]