Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PINX1. AA range:121-170
Subcellular Location
Nucleus . Nucleus, nucleolus. Chromosome, telomere. Chromosome, centromere, kinetochore. Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to the kinetochore is mediated by its central region and depends on N
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
54984
Other Name
LPTL
LPTS
Liver-related putative tumor suppressor
PIN2/TERF1-interacting telomerase inhibitor 1
PINX1
Pin2-interacting protein X1
Protein 67-11-3
TRF1-interacting protein 1
LPTS
Liver-related putative tumor suppressor
PIN2/TERF1-interacting telomerase inhibitor 1
PINX1
Pin2-interacting protein X1
Protein 67-11-3
TRF1-interacting protein 1
Background
domain:The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activity.,function:Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.,similarity:Belongs to the PINX1 family.,similarity
expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.,
expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.,