Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
IF
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MARCH5. AA range:21-70
Subcellular Location
Mitochondrion outer membrane
Multi-pass membrane protein . Authors show that the protein can be detected in endoplasmic reticulum (PubMed:14722266). Authors (PubMed:16874301) show its presence only in mitochondria (PubMed:16874301). .
Multi-pass membrane protein . Endoplasmic reticulum membrane
Multi-pass membrane protein . Authors show that the protein can be detected in endoplasmic reticulum (PubMed:14722266). Authors (PubMed:16874301) show its presence only in mitochondria (PubMed:16874301). .
Multi-pass membrane protein . Endoplasmic reticulum membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
54708
Observed Band
37kD
Other Name
E3 ubiquitin-protein ligase MARCH5
MARCH-V
MARCH5
MITOL
Membrane-associated RING-CH protein V
Membrane-associated RING finger protein 5
Mitochondrial ubiquitin ligase
RING finger protein 153
RNF153
MARCH-V
MARCH5
MITOL
Membrane-associated RING-CH protein V
Membrane-associated RING finger protein 5
Mitochondrial ubiquitin ligase
RING finger protein 153
RNF153
Background
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2
MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008],
MIM 608507) and DRP1 (DNM1L
MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008],
MIM 608507) and DRP1 (DNM1L