Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ATP7B. AA range:161-210
Subcellular Location
Golgi apparatus, trans-Golgi network membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Late endosome . Predominantly found in the trans-Golgi network (TGN). Localized in the trans-Golgi network under low copper conditions, redistributes to cytoplasmic vesicles when cells are exposed to elevated copper levels, a
[Isoform 1]: Golgi apparatus membrane
[Isoform 2]: Cytoplasm .
[WND/140 kDa]: Mitochondrion .
Multi-pass membrane protein .
Multi-pass membrane protein . Late endosome . Predominantly found in the trans-Golgi network (TGN). Localized in the trans-Golgi network under low copper conditions, redistributes to cytoplasmic vesicles when cells are exposed to elevated copper levels, a
[Isoform 1]: Golgi apparatus membrane
[Isoform 2]: Cytoplasm .
[WND/140 kDa]: Mitochondrion .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
540
Other Name
ATP7B
Copper-transporting ATPase 2
Copper pump 2
PWD
WC1
WND
Wilson disease-associated protein
Copper-transporting ATPase 2
Copper pump 2
PWD
WC1
WND
Wilson disease-associated protein
Background
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This prote