Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ATP7A. AA range:591-640
Subcellular Location
Golgi apparatus, trans-Golgi network membrane
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, postsynaptic density . Cycles constitutively between the TGN and the plasma membrane (PubMed:9147644). Predominantly found in the TGN and relocalized
Multi-pass membrane protein . Early endosome membrane
Multi-pass membrane protein . Melanosome membrane
[Isoform 3]: Cytoplasm, cytosol .
[Isoform 5]: Endoplasmic reticulum .
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, postsynaptic density . Cycles constitutively between the TGN and the plasma membrane (PubMed:9147644). Predominantly found in the TGN and relocalized
Multi-pass membrane protein . Early endosome membrane
Multi-pass membrane protein . Melanosome membrane
[Isoform 3]: Cytoplasm, cytosol .
[Isoform 5]: Endoplasmic reticulum .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
538
Other Name
ATP7A
Copper-transporting ATPase 1
Copper pump 1
MC1
MNK
Menkes disease-associated protein
Copper-transporting ATPase 1
Copper pump 1
MC1
MNK
Menkes disease-associated protein
Background
ATPase copper transporting alpha(ATP7A) Homo sapiens This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-d