Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SHC3. AA range:291-340
Subcellular Location
cytosol,plasma membrane,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
53358
Observed Band
48kD
Other Name
N-Shc
NSHC
Neuronal Shc
Protein Rai
SH2 domain protein C3
SHC-transforming protein 3
SHC-transforming protein C
SHC3
SHCC
Src homology 2 domain-containing-transforming protein C3
Background
function:Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.,PTM:Tyrosine phosphorylated.,similarity:Co