Información del producto
PLC γ1 (phospho Tyr1253) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PLCG1 around the phosphorylation site of Tyr1253. AA range:1221-1270
Subcellular Location
Cell projection, lamellipodium . Cell projection, ruffle . Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5335
Observed Band
150kD
Other Name
1-phosphatidylinositol 4
5-bisphosphate phosphodiesterase gamma-1
PLC-148
PLC-II
PLC-gamma-1
PLC1
PLCG1
Phosphoinositide phospholipase C-gamma-1
Phospholipase C-II
Phospholipase C-gamma-1
5-bisphosphate phosphodiesterase gamma-1
PLC-148
PLC-II
PLC-gamma-1
PLC1
PLCG1
Phosphoinositide phospholipase C-gamma-1
Phospholipase C-II
Phospholipase C-gamma-1
Background
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction