Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MARCH2. AA range:191-240
Subcellular Location
Endoplasmic reticulum membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Cytoplasm . Cell membrane
Multi-pass membrane protein . Endosome membrane
Multi-pass membrane protein . Golgi apparatus membrane
Multi-pass membrane protein . Lysosome membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Cytoplasm . Cell membrane
Multi-pass membrane protein . Endosome membrane
Multi-pass membrane protein . Golgi apparatus membrane
Multi-pass membrane protein . Lysosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
51257
Other Name
E3 ubiquitin-protein ligase MARCH2
HSPC240
MARCH-II
MARCH2
Membrane-associated RING-CH protein II
Membrane-associated RING finger protein 2
RING finger protein 172
RNF172
HSPC240
MARCH-II
MARCH2
Membrane-associated RING-CH protein II
Membrane-associated RING finger protein 2
RING finger protein 172
RNF172
Background
MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. M
Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010],
Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010],