Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TM16G. AA range:881-930
Subcellular Location
Multi-pass membrane protein . Cell junction . Endoplasmic reticulum . Concentrates at sites of cell-cell contact (PubMed:17308099). Shows an intracellular localization according to PubMed:22075693 and PubMed:20056604. .
[Isoform 1]: Cell membrane
[Isoform 2]: Cytoplasm, cytosol .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
50636
Observed Band
105kD
Other Name
ANO7
Anoctamin-7
D-TMPP
Dresden transmembrane protein of the prostate
IPCA-5
NGEP
New gene expressed in prostate
PCANAP5
Prostate cancer-associated protein 5
TMEM16G
Transmembrane protein 16G
Background
This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different