Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PAK1/2/3. AA range:111-160
Subcellular Location
Cytoplasm . Cell junction, focal adhesion . Cell projection, lamellipodium . Cell membrane . Cell projection, ruffle membrane . Cell projection, invadopodium . Nucleus, nucleoplasm . Chromosome . Cytoplasm, cytoskeleton, microtubule organizing center, cen
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5058/5062/5063
Other Name
Alpha-PAK
Gamma-PAK
OPHN3
PAK-1
PAK-2
PAK1
PAK2
PAK3
PAK65
S6/H4 kinase
Serine/threonine-p
Serine/threonine-protein kinase PAK 1
Serine/threonine-protein kinase PAK 2
p21-activated kinase 1
p21-activated kinase 2
p58
p65-PAK
Background
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small G