Información del producto
PAKα (phospho Ser199) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PAK1 around the phosphorylation site of Ser199. AA range:165-214
Subcellular Location
Cytoplasm . Cell junction, focal adhesion . Cell projection, lamellipodium . Cell membrane . Cell projection, ruffle membrane . Cell projection, invadopodium . Nucleus, nucleoplasm . Chromosome . Cytoplasm, cytoskeleton, microtubule organizing center, cen
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Rat
Monkey
Mouse
Rat
Human Gen
5058
Observed Band
61kD
Other Name
Alpha-PAK
PAK-1
PAK1
Serine/threonine-protein kinase PAK 1
p21-activated kinase 1
p65-PAK
PAK-1
PAK1
Serine/threonine-protein kinase PAK 1
p21-activated kinase 1
p65-PAK
Background
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small G